Noninvasive Blood Perfusion Measurements of an Isolated Rat Liver and an Anesthetized Rat Kidney
نویسندگان
چکیده
منابع مشابه
Isolated Perfusion of the Rat Liver
The isolated perfused rat liver (IPRL) has proven to be a useful model for the study qf physiology and pathology of the liver, For research in nonparenchymal cell (NPC) function that includes measurement of cytokine production (eg, TNF), it is necessary to have a sterilized perfusion system, We have modified the IPRL apparatus so as to be able to perform sterile perfusions of two livers simulta...
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Objective(s) This study aimed to investigate and to compare the effects of nifedipine and amlodipine, dihydropyridine (DHP) calcium channel blockers (CCBs) on perfusion pressure of isolated perfused rat kidney. Materials and Methods Following the establishment of renal perfusion with a constant baseline pressure of 85-95 mmHg, the renal vasculature was constricted by phenylephrine (PE) injec...
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15 صفحه اولAn optimized model for rat liver perfusion studies.
Conditions which influence the viability, integrity, and extraction efficiency of the isolated perfused rat liver were examined to establish optimal conditions for subsequent work in reperfusion injury studies including the choice of buffer, use of oncotic agents, hematocrit, perfusion flow rate, and pressure. Rat livers were perfused with MOPS-buffered Ringer solution with or without erythrocy...
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ژورنال
عنوان ژورنال: Journal of Biomechanical Engineering
سال: 2008
ISSN: 0148-0731,1528-8951
DOI: 10.1115/1.2978989